Principal Scientist , Analytical Science Lead (Boston) Job at Metric Bio, Boston, MA

T0VBSnZmUkc1TzhrMXo1Qlg3UHd0RGxY
  • Metric Bio
  • Boston, MA

Job Description

Principal Scientist , Analytical Science Lead

Principal Scientist , Analytical Science Lead

We are seeking an experienced and visionary Analytical Science Lead to lead the development and execution of robust analytical strategies for characterizing biomaterials cultivated in plant cell culture systems. In this pivotal role, you will serve as the strategic and technical lead for analytical development, guiding a growing team in establishing and scaling world-class capabilities across metabolite profiling, compound characterization, and process analytics to ensure the quality, consistency, and scalability.

This is a hands-on, senior-level position ideal for a scientifically curious leader with deep technical fluency in analytical chemistry, method development, and data interpretation. Your work will directly influence R&D direction, production efficiency, and product quality, helping us accelerate the transition to sustainable biomaterials grown from cells.

RESPONSABILITIES

Scientific Leadership & Strategy

  • Serve as the technical lead in analytical development across our R&D and production teams.
  • Develop fit-for-purpose testing strategies to support R&D, process development and quality assurance.
  • Design and oversee high-impact experiments that enable accurate quantification and structural analysis of biomolecules (e.g., proteins, polysaccharides, small molecules).
  • Guide scientific direction through hypothesis-driven experimentation and data-informed insights.
  • Provide strategic inputs into scale-up, regulatory, and commercialization efforts from an analytical science perspective.
  • Lead and develop a high-performing analytical team, including junior scientists and research associates.
  • Train staff on advanced analytical techniques and experimental design, fostering a learning oriented culture.
  • Provide expert input on experimental planning, execution, and troubleshooting

Process Optimization & Innovation

  • Drive innovation in analytical workflows, improving sensitivity, speed, and reproducibility of data acquisition.
  • Lead cross-functional process improvement initiatives, collaborating with R&D and process development and production teams.
  • Identify and implement scalable, cost-effective analytical solutions to support rapid iteration and commercialization.
  • Establish and maintain documentation and compliance workflows in line with food safety standards and certification frameworks as required
  • Champion robust data analysis practices, including development of novel models and tools for interpretation.
  • Translate complex datasets into actionable insights for R&D and business decision-making.
  • Proactively monitor scientific trends and translate them into strategic opportunities.

Lab Excellence & Compliance

  • Lead best practices in lab operations, from safety protocols to equipment selection and usage.
  • Provide hands-on and advisory support for waste management, PPE adherence, and lab safety training.

QUALIFICATIONS

Required Qualifications

  • PhD in Analytical Chemistry, Biochemistry, Chemical Engineering, Biotechnology, or a related scientific discipline.
  • 8+ years of industry experience in analytical method development, including 3+ years in a leadership role.
  • Proven expertise in analytical techniques such as HPLC/UPLC, UV-Vis, FTIR, and spectroscopy, with a focus on complex biological systems.
  • Demonstrated ability to build and implement compliant analytical workflows aligned with food safety, quality, and regulatory standards.
  • Hands-on experience in biomolecular and material characterization relevant to fermentation based or cell-derived products.
  • Familiarity with physical and chemical analysis methods such as GPC/SEC, rheology, XRD, and TGA, particularly for fiber and cellulosic material applications.
  • Excellent leadership, project management, and interpersonal communication skills.
  • Strong commitment to sustainability, safety, and scientific rigor.

PREFERRED QUALIFICATIONS

  • Experience in cellular agriculture, synthetic biology, or early-stage biotechnology environments.
  • Background in metabolite profiling, plant cell culture analytics, or biologics characterization.
  • Knowledge of LC-MS and GC-MS techniques is a plus, especially for cocoa-related metabolite analysis.
  • Familiarity with textile-relevant material science assays, including mechanical and rheological testing of natural or engineered fibers.
  • Understanding of regulatory frameworks in the food, textile, or biomaterials industries.
  • Visionary leadership with hands-on technical fluency.
  • Strong mentorship mindset with a passion for developing scientific talent.
  • Data-driven and systems thinker with an eye for emerging technologies.
  • Collaborative, strategic, and proactive in cross-functional settings.
  • Excellent written and verbal communication for both technical and non-technical audiences.

What We Offer

  • The opportunity to shape the analytical foundation and influence scientific strategy
  • Full-time benefits including medical, dental, and vision coverage
  • Life and disability insurance
  • 401(k) plan with company match
  • Generous paid vacation and holidays
  • A mission-driven culture that values science, innovation, and sustainability

Seniority level

  • Seniority level

    Mid-Senior level

Employment type

  • Employment type

    Full-time

Job function

  • Job function

    Science

Referrals increase your chances of interviewing at Metric Bio by 2x

Get notified about new Analytical Scientist jobs in Boston, MA .

Analytical Method Development Scientist & Team Lead – GMP Environment

Billerica, MA $122,500.00-$155,000.00 6 days ago

Senior Scientist, Perfusion Mammalian Cell Culture

KRI R&D Research Scientist I/II, Chemist

Lexington, MA $127,500.00-$195,600.00 2 weeks ago

Cambridge, MA $84,000.00-$121,333.33 2 days ago

Cambridge, MA $55,461.00-$69,333.00 2 weeks ago

Principle Scientist, Antibody Engineering / Structural Biology

Senior Scientist, Analytical Development (AD)

Lexington, MA $137,000.00-$215,270.00 1 week ago

Clinical & Regulatory Medical Writing Manager (Hybrid)

Senior Scientist II PET Analytical Development

QC Scientist Analytical Method Validation

Lexington, MA $99,500.00-$156,420.00 5 days ago

Framingham, MA $84,000.00-$121,333.33 1 week ago

Scientist, Formulations (Delivery Chemistry)

Analytical Scientist – Bioprocess Support

Associate Scientist I - Global Drug Discovery

Lexington, MA $81,010.00-$145,820.00 2 days ago

Cambridge, MA $122,250.00-$176,583.33 6 days ago

Sr. Research Associate - Formulation Scientist

Lexington, MA $68,370.00-$119,650.00 1 week ago

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

#J-18808-Ljbffr

Job Tags

Full time,

Similar Jobs

Global Cities, Inc.

Chief Academic Officer Job at Global Cities, Inc.

 ...steps towards becoming the leaders we need to solve the complex problems our world faces. About the Role The Chief Academic Officer (CAO) works closely with the President and Senior Leadership Team to strengthen and advance Global Cities partnerships in public... 

Aspen Dental

Dental Assistant - Entry level Job at Aspen Dental

At Aspen Dental, we put You First, offering the security and job stability that comes with working with a world-class dental...  ...you thrive in your career. When you join our team as an Entry-Level Dental Assistant , you will have the opportunity to give back to communities... 

LOGISTEED America, Inc.

Licensed Customs Broker Job at LOGISTEED America, Inc.

 ...transportation and logistics services and help make the world a better place for generations to come. We are looking for a Licensed Licensed Customs Broker to join us on this mission! Location: Elk Grove Village, IL WHO WE ARE: Founded in 1950, LOGISTEED-America is... 

Legacy Health

Radiologic Technologist (Rad Tech) Job at Legacy Health

 ...As a Radiologic Technologist, your work involves much more than performing diagnostic exams; you also ensure a positive experience by making patients feel respected and secure. If this is how you view your job, we invite you to consider a career with Legacy.... 

Bring It Home

Program & Operations Manager Job at Bring It Home

 ...Job Title: Program & Operations Manager Location: Northwest Arkansas (remote-first, with regular local presence) Salary: $75,000/year plus employer-paid health insurance Type: Full-Time, Exempt About Bring It Home Bring it Home is a dynamic non-profit organization...