Vice President, Biology and Translational Research (San Francisco) Job at GondolaBio, San Francisco, CA

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  • GondolaBio
  • San Francisco, CA

Job Description

Vice President, Biology and Translational Research

Join to apply for the Vice President, Biology and Translational Research role at GondolaBio

Vice President, Biology and Translational Research

Join to apply for the Vice President, Biology and Translational Research role at GondolaBio

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This range is provided by GondolaBio. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$313,000.00/yr - $355,000.00/yr

About Gondola Bio:

GondolaBio is a clinical-stage biopharmaceutical company focused on developing next-generation therapeutics for genetic diseases. Originally launched as BridgeBioX, a subsidiary of BridgeBio, GondolaBio secured $300M in private financing from external investors in 2024 and became an independent company within the BridgeBio ecosystem. The company aims to leverage cutting-edge biological research to create breakthrough medicines addressing high unmet needs across multiple therapeutic areas, including neurology, pulmonology, cardiology, nephrology, and endocrinology. Located on the Stanford Life Sciences campus, GondolaBio fosters a unique hybrid environment where top scientists from around the world collaborate with senior leadership and advisors, blending industry expertise with academic innovation.

Portal Therapeutics is an early clinical stage biotechnology company, and the lead program in GondolaBio’s portfolio. Portal is developing a novel potential best-in-class therapy for erythropoietic protoporphyria, a severe genetic disease of the blood which results in extreme sensitivity to sunlight and liver damage.

Who You Are:

We seek an experienced entrepreneurial scientist to drive the biology and translational research for Portal Therapeutics. You will lead scientific strategy and direction, assay development, mouse model experimentation, preclinical dose guidance, regulatory document writing, and other translational biology and pharmacology experiments through a combination of internal and external efforts. This job requires excellent communication and interpersonal skills as well as technical and scientific abilities.

Responsibilities:

  • Lead the biology, pharmacology, and translational research for Portal
  • Develop a deep understanding of the biology and pharmacology of the relevant disease area and treatment approaches, and be able to communicate these concepts internally and externally
  • Responsible for generating a comprehensive biology and pharmacology package to support US and international regulatory filings
  • This individual will be responsible for the design, execution, and interpretation of preclinical studies to address mechanism of action and translational pharmacology studies (in vitro and in vivo)
  • Manage relationships with CROs for efficient execution of all the preclinical and translational studies
  • Collaborate with cross-functional teams, including DMPK, toxicology, clinical development and regulatory to advance our therapeutic candidates from preclinical stages through clinical development in a fast-paced, dynamic environment
  • Develop scientific publications, abstracts, and posters, and investor and layperson-facing materials on the Portal program
  • Evaluate expansion indications or additional therapy opportunities
  • Represent the program scientifically to internal and external audiences, including investors and the Board of Directors
  • Manage research associates or scientists as needed
  • Contribute to the drafting of translation- and pharmacology-related sections of regulatory documents including Investigator’s Brochure, clinical protocols, and briefing books
  • Contribute to due diligence and gap analysis on potential new GondolaBio assets

No matter your role at BridgeBio, successful team members are:

  • Patient Champions, who put patients first and uphold strict ethical standards
  • Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset
  • Truth Seekers, who are detailed, rational, and humble problem solvers
  • Individuals Who Inspire Excellence in themselves and those around them
  • High-quality executors, who execute against goals and milestones with quality, precision, and speed

Education, Experience & Skills Requirements:

  • Ph.D., MD,or Ph.D./MD degree and expertise in a relevant scientific field with 8+ years of related work experience in pharma or biotech environment
  • Strong scientific background and achievements in bioscience and translational, ideally demonstrated by scientific publications, presentations, and/or patents
  • Proven track record of successfully leading research programs and teams
  • Strong understanding of drug discovery and development processes
  • Excellent communication, leadership, and organizational skills
  • Ability to think strategically and execute effectively
  • Experience in collaborating with cross-functional teams and external partners
  • Knowledge of regulatory requirements and industry standards
  • Demonstrate creative 'out of the box' thinking to solve complex technical problems and champion innovative technologies to achieve project goals
  • Commitment, drive, and ownership mindset

What We Offer:

  • Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts
  • A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
  • An unyielding commitment to always putting patients first. Learn more about how we do this here
  • A de-centralized model that enables our program teams to focus on advancing science and helping patients. Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science
  • A place where you own the vision – both for your program and your own career path
  • A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
  • Access to learning and development resources to help you get in the best professional shape of your life
  • Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
  • Flexible PTO
  • Rapid career advancement for strong performers
  • Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time
  • Partnerships with leading institutions
  • Commitment to Diversity, Equity & Inclusion

At GondolaBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. GondolaBio is a multi-state employer, and this salary range may not reflect positions based in other states.

Seniority level

  • Seniority level

    Executive

Employment type

  • Employment type

    Full-time

Job function

  • Job function

    Science

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Job Tags

Full time, Work experience placement, Flexible hours,

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